ncRNA name | factor B siRNA |
ncRNA Category | siRNA |
Disease name | choroidal neovascularization (CNV) |
Species | Mus musculus |
Tissues/Cell_line | RPE-choroid-scleral tissues, serum |
Methods | siRNA injection, immunohistochemistry, RT-PCR, Western blot |
Expression pattern | associated |
Functional description | Inhibition of the alternative pathway by factor B siRNA resulted in decreased levels of membrane attack complex and angiogenic factors-vascular endothelial growth factor and TGF-beta2. |
PubMed ID | 16849499 |
Year | 2006 |
Title | Complement activation via alternative pathway is critical in the development of laser-induced choroidal neovascularization: role of factor B and factor H. |
Drug-related ncRNA | NO |
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